Press and Publications

Peer-reviewed research, clinical trial updates and media resources

Publications and Clinical Trials

AlcoChange is supported by a growing body of peer-reviewed evidence and ongoing clinical research backed by the NHS, NIHR and academic partnerships since 2012.

Peer-Reviewed

Feasibility study of a digital therapeutic for alcohol-related liver disease

Mehta et al., JHEP Reports, 2024;6(4):100993

A single-centre feasibility pilot conducted at the Royal Free London NHS Foundation Trust, evaluating the AlcoChange digital therapeutic in 65 adults with alcohol-related liver disease. The study demonstrated feasibility of delivering a 90-day digital behaviour change programme within routine hepatology care.

RCT Protocol

AlcoChange randomised controlled trial protocol

Cook et al., published protocol

The published protocol for the NIHR-funded, multi-centre randomised controlled trial of AlcoChange. The protocol describes the trial design, outcome measures and statistical analysis plan for evaluating the digital therapeutic against standard care.

Ongoing

NIHR-funded multi-centre randomised controlled trial

ISRCTN10911773, 25 NHS Trusts, n=324

A large-scale, NIHR-funded randomised controlled trial conducted across 25 NHS Trusts with 324 patients recruited. The trial evaluates AlcoChange as an adjunct to standard clinical care. Results are expected Q3 to Q4 2026.

Research Heritage

Over a decade of collaboration with leading NHS trusts and academic institutions

AlcoChange has been developed through sustained collaboration between CyberLiver Limited, the NHS and academic research partners since 2012. This work has been supported by funding from the National Institute for Health and Care Research (NIHR), contributing to the design, clinical evaluation and iterative refinement of the digital therapeutic.

The programme of research spans feasibility studies, protocol development and a definitive multi-centre randomised controlled trial, reflecting a rigorous, evidence-led approach to digital health innovation in hepatology.

Press and Media Enquiries

For press enquiries, interview requests or media resources, please get in touch with our communications team.

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